Tunable carbon-carbon and carbon-sulfur cross-coupling of boronic acids with 3,4-dihydropyrimidine-2-thiones.
نویسندگان
چکیده
Direct microwave-assisted Pd(0)-catalyzed/Cu(I)-mediated carbon-carbon cross-coupling of 3,4-dihydropyrimidine-2-thiones and boronic acids under Liebeskind-Srogl conditions leads to 2-aryl-1,4-dihydropyrimidines in moderate to high yield. In contrast, Cu(II)-mediated reaction of the same substrates leads to carbon-sulfur cross-coupling. [reaction: see text]
منابع مشابه
Unveiling the role of boroxines in metal-free carbon–carbon homologations using diazo compounds and boronic acids† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c7sc02264f, additional data is available from the University of Cambridge Data Repository Website: https://doi.org/10.17863/CAM.10823.
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ورودعنوان ژورنال:
- Organic letters
دوره 6 5 شماره
صفحات -
تاریخ انتشار 2004